Pulse Physiology Engine

The Pulse Physiology Engine is an open source library for accurate, consistent, dynamic simulation of the whole-body response to injury, disease, and treatment.

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Description

The Pulse Physiology Engine can be used as a standalone library or integrated with simulators, sensor interfaces, and models of all fidelities. The platform includes a common data model for standard model and data definitions, a software interface for engine control, robust physics-based circuit and transport solvers, and a verification and validation suite. The architecture was specifically designed to reduce model development time and increase the usability of the engine in simulations by creating a modular, extensible definition for human physiology. Pulse provides the following benefits to its user community:

Pulse is comprised of numerical models representing the different body systems, feedback mechanisms and interactions between the systems, PK/PD, and medical equipment. The major systems are modeled using zero-dimensional lumped-parameter circuit analogs (e.g., the cardiovascular circuit) with homeostatic feedback. The differential equations contained in each system are calculated through transient analysis with a shared dynamic time step. The numerical models currently execute with a time step of 20 ms, which can be reduced, as necessary, to ensure all physiology features of interest are captured, while maintaining real-time execution for the simulation.

Technical Details

(Please include a full, comprehensive list of the features of the product)

Code Modules: (Please include a full list of each Plugin module and their module type (Runtime, Editor etc.))

Number of Blueprints: 1

Number of C++ Classes: 2

Network Replicated: No

Supported Development Platforms: Win64

Supported Target Build Platforms: Win64

Documentation: https://pulse.kitware.com/_docs.html

Example Project: https://gitlab.kitware.com/physiology/unreal

Important/Additional Notes: https://gitlab.kitware.com/physiology/engine

Supported Engine Versions

5.0